Losing Myelin Scrambles the Brain’s Sensory Signals

Losing Myelin Scrambles the Brain’s Sensory SignalsNew research reveals that even a small loss of myelin—the protective coating around neurons—can severely disrupt how the brain sends and interprets sensory information. Studying corticothalamic circuits in mice, scientists found that when the first segment of myelin closest to the neuron’s cell body was degraded, nerve signals slowed and lost their crucial “first wave,” altering how sensory information was encoded.